Cholera is a severe diarrheal disease caused by Vibrio cholerae, typically transmitted through contaminated water or food. The bacteria produce a toxin that leads to intense fluid loss and dehydration. Cholera toxin antibody plays a crucial role in neutralizing this toxin and is essential for developing vaccines and therapies. Cholera medication often includes antibiotics to treat cholera such as doxycycline or azithromycin, alongside rehydration therapies to manage symptoms and prevent complications. Cholera antibody testing can aid in diagnosis and monitoring. Effective cholera disease treatment involves addressing both symptoms and underlying causes, emphasizing the importance of timely medical intervention.